报告题目: Selenium Nucleic Acids for Chemical & Structural Biology and Drug Discovery 

 报告人: Prof. Zhen Huang 

 时间: 2015年4月28日(周二)   上午10:00 

 地点: 生物所高新区5楼会议室 

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 报告人简介: 

 Prof. Zhen Huang (Ph.D.) was born in 1964 and raised in Sichuan, China. He received his B.S. degree from Sichuan University in 1984, M.S. from Peking University in 1987, and Ph.D. degree from Swiss Federal Institute of Technology in 1994. In 1994, he joined the Department of Genetics at Harvard Medical School as a research fellow, in Laboratory of Professor Jack Szostak (Nobel Laureate in Medicine in 2009). He was hired in 1998 by Brooklyn College, City University of New York, as assistant professor and was later promoted to associate professor with tenure. In 2004, Dr. Huang was recruited to Chemistry Department, Georgia State University, is Professor of Chemistry and Chemical Biology, and is also University Distinguished Professor Awardee of Georgia State University.  

 He has pioneered and developed selenium and tellurium derivatizations of nucleic acids for structure and function studies of nucleic acids, protein-nucleic acid complexes, and nucleic acid-small molecular ligands. His current research interests are in selenium and tellurium derivatizations of DNAs and RNAs for X-ray crystallographic studies of nucleic acids and protein complexes, synthesis of analogs of nucleosides and nucleotides for structure, function and anticancer studies, development of RNA microchip technology for direct detection and quantitation of gene expression profile for Cancer Early Detection, nanomaterial-assisted novel RNA microchip, modified nucleic acid-based nano-medicine, nucleic acid-based cancer diagnosis, in vitro selection, evolution and characterization of ligand-binding and catalytic RNAs and DNAs.